Barriers to intravenous penicillin use for treatment of nonmeningitis pneumococcal disease.
نویسندگان
چکیده
Infectious disease physicians were surveyed to determine whether the new penicillin breakpoint change will translate into increased penicillin use and to identify barriers to intravenous (i.v.) penicillin use for pneumococcal infections. The inconvenience of i.v. penicillin may limit its use despite a reduction in numbers of infections considered resistant.
منابع مشابه
Penicillin-resistant pneumococcus and risk of treatment failure in pneumonia.
OBJECTIVE To determine whether the presence of in vitro penicillin-resistant Streptococcus pneumoniae increases the risk of clinical failure in children hospitalised with severe pneumonia and treated with penicillin/ampicillin. DESIGN Multicentre, prospective, observational study. SETTING 12 tertiary-care centres in three countries in Latin America. PATIENTS 240 children aged 3-59 months,...
متن کاملClinical outcome of pneumococcal meningitis during the emergence of pencillin-resistant Streptococcus pneumoniae: an observational study
BACKGROUND Prior to the availability of generic third-generation cephalosporins, penicillins were widely used for treatment of pneumococcal meningitis in developing countries despite concerns about rising levels of penicillin resistance among pneumococcal isolates. We examined the impact of penicillin resistance on outcomes of pneumococcal meningitis over a ten year period in an infectious dise...
متن کاملشیوع ناقلین حلقی پنوموکوک و الگوی مقاومت آن در بین کودکان مهدکودک‌های شهر یزد
Introduction: Streptococcus pneumoniae is one of the most important causes of pneumonia, meningitis and septicemia. Decades after successful treatment of this infection with penicillin, frequency of penicillin resistance is reportedly on the rise throughout the world. This cross sectional study was designed in Yazd to determine the prevalence of pneumococcal pharyngeal carriers and its succept...
متن کاملPneumococcaemia complicated by meningitis.
Meningitis developed in 3 of 14 children with occult pneumococcaemia; in 2 of them it developed while they were being treated with low doses of intravenous penicillin, in the third child it developed at a time when he was not being treated. All children with occult pneumococcaemia should be treated with intravenous penicillin as are those with pneumococcal meningitis.
متن کاملMultivariate analysis of risk factors for infection due to penicillin-resistant and multidrug-resistant Streptococcus pneumoniae: a multicenter study.
Pneumococcal disease was studied prospectively to determine the risk factors associated with resistance to penicillin and other antibiotics. One hundred twelve clinically significant pneumococcal isolates were recovered from 95 patients. Approximately one-half (49.47%) of the cases were due to penicillin-resistant strains. Multivariate analysis showed that previous use of beta-lactam antibiotic...
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عنوان ژورنال:
- Journal of clinical microbiology
دوره 48 9 شماره
صفحات -
تاریخ انتشار 2010